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F Holsboer Selected Research

Corticotropin-Releasing Hormone

11/2015Evidence for the role of corticotropin-releasing factor in major depressive disorder.
11/2008Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.
9/2006Growth hormone-releasing hormone and corticotropin-releasing hormone enhance non-rapid-eye-movement sleep after sleep deprivation.
1/2003The role of peptides in treatment of psychiatric disorders.
1/2003The high-affinity non-peptide CRH1 receptor antagonist R121919 attenuates stress-induced alterations in plasma oxytocin, prolactin, and testosterone secretion in rats.
8/2002Mice overexpressing CRH show reduced responsiveness in plasma corticosterone after a5-HT1A receptor challenge.
1/2002Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice.
7/2001CRHR1 antagonists as novel treatment strategies.
5/2001The combined dexamethasone-suppression/CRH-stimulation test in alcoholics during and after acute withdrawal.
5/2001Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders.
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F Holsboer Research Topics

Disease

8Anxiety Disorders (Anxiety Disorder)
04/2013 - 05/2000
8Mood Disorders (Mood Disorder)
07/2010 - 05/2001
7Mental Disorders (Mental Disorder)
09/2008 - 09/2000
6Panic Disorder (Panic Attack)
09/2011 - 03/2000
4Depressive Disorder (Melancholia)
11/2016 - 11/2006
4Sleep Wake Disorders
03/2014 - 10/2000
3Major Depressive Disorder (Major Depressive Disorders)
11/2015 - 03/2001
3Multiple Sclerosis
06/2012 - 04/2001
3Neuroblastoma
09/2004 - 04/2000
3Inflammation (Inflammations)
08/2001 - 01/2001
2Genetic Predisposition to Disease (Genetic Predisposition)
02/2014 - 06/2012
2Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
09/2010 - 01/2000
2Sleep Deprivation
02/2010 - 09/2006
2Seizures (Absence Seizure)
10/2008 - 05/2000
2Cushing Syndrome
11/2006 - 01/2001
2Schizophrenia (Dementia Praecox)
01/2003 - 10/2000
2Infections
01/2001 - 12/2000
2Body Weight (Weight, Body)
12/2000 - 06/2000
1Hemangioblastoma
09/2015
1Carcinoma (Carcinomatosis)
09/2015
1Pheochromocytoma
09/2015
1Neoplasms (Cancer)
09/2015
1Shock
09/2010
1Memory Disorders (Memory Loss)
07/2010
1Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2010
1Neuroinflammatory Diseases
10/2008
1Disease Susceptibility (Diathesis)
04/2008
1Drug-Related Side Effects and Adverse Reactions
01/2005
1Hypopituitarism (Sheehan's Syndrome)
08/2004
1Hypothermia
08/2002
1Nausea
11/2001

Drug/Important Bio-Agent (IBA)

14Corticotropin-Releasing HormoneIBA
11/2015 - 01/2000
7Antidepressive Agents (Antidepressants)IBA
01/2009 - 09/2000
6GlucocorticoidsIBA
11/2003 - 01/2000
4Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA
02/2014 - 01/2001
4Hormones (Hormone)IBA
02/2010 - 01/2000
3Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
04/2013 - 05/2000
3NeurosteroidsIBA
01/2005 - 11/2001
3SteroidsIBA
11/2001 - 05/2000
3Adrenal Cortex Hormones (Corticosteroids)IBA
11/2001 - 05/2000
3TetragastrinIBA
09/2001 - 01/2000
3CytokinesIBA
08/2001 - 01/2001
3Adrenocorticotropic Hormone (ACTH)FDA Link
05/2001 - 01/2000
3Hydrocortisone (Cortisol)FDA LinkGeneric
03/2001 - 01/2000
2Pharmaceutical PreparationsIBA
06/2012 - 01/2005
2NeuropeptidesIBA
09/2011 - 01/2003
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2009 - 05/2001
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2008 - 11/2006
2Dehydroepiandrosterone (DHEA)IBA
01/2005 - 12/2000
2LeptinIBA
01/2005 - 10/2000
2Growth Hormone (Somatotropin)IBA
08/2004 - 02/2001
2Anti-Anxiety Agents (Anxiolytics)IBA
11/2003 - 09/2001
2Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
11/2003 - 09/2000
2Atrial Natriuretic Factor (ANF)IBA
11/2003 - 09/2001
2LigandsIBA
11/2003 - 09/2001
2CorticosteroneIBA
08/2001 - 05/2000
2Steroid Receptors (Steroid Receptor)IBA
04/2001 - 01/2001
1Oxygen (Dioxygen)IBA
09/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2015
1Tacrolimus Binding Proteins (FKBP)IBA
04/2013
1InterferonsIBA
06/2012
1Immunomodulating AgentsIBA
06/2012
1AntibodiesIBA
06/2012
1beta CateninIBA
09/2010
1Glycogen Synthase Kinase 3 betaIBA
09/2010
1Transcription Factors (Transcription Factor)IBA
09/2010
1Phosphotransferases (Kinase)IBA
09/2010
1Brain-Derived Neurotrophic Factor (BDNF)IBA
07/2010
1Tryptophan HydroxylaseIBA
07/2010
1gamma-Aminobutyric Acid (GABA)IBA
05/2010
1GATIBA
06/2009
1GABA Plasma Membrane Transport ProteinsIBA
06/2009
1Proteins (Proteins, Gene)FDA Link
04/2009
1Kainic Acid (Kainate)IBA
10/2008
1Biomarkers (Surrogate Marker)IBA
09/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2008
1HLA Antigens (Human Leukocyte Antigens)IBA
04/2008
1Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
09/2006
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2005
1Flupenthixol (Flupentixol)IBA
09/2004
1Haloperidol (Haldol)FDA LinkGeneric
09/2004
1Clozapine (Clozaril)FDA LinkGeneric
09/2004
1Risperidone (Risperdal Consta)FDA LinkGeneric
09/2004
1PhenothiazinesIBA
09/2004
1Atrial Natriuretic Factor Receptors (Atrial Natriuretic Factor Receptor)IBA
11/2003
1Sodium LactateFDA LinkGeneric
11/2003
1Substance PIBA
01/2003
1Vasopressins (Vasopressin)IBA
01/2003
1Hypnotics and Sedatives (Sedatives)IBA
01/2003
1NeurotensinIBA
01/2003
1Peptides (Polypeptides)IBA
01/2003
1Antipsychotic Agents (Antipsychotics)IBA
01/2003
18-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)IBA
08/2002
1Neurotransmitter Agents (Neurotransmitter)IBA
08/2002
1AutoreceptorsIBA
08/2002
1Glial Fibrillary Acidic ProteinIBA
11/2001
15-HT3 Serotonin Receptors (5 HT3 Receptor)IBA
11/2001
1Eosine Yellowish-(YS) (Eosin)IBA
11/2001

Therapy/Procedure

6Therapeutics
11/2016 - 04/2000
1Drug Therapy (Chemotherapy)
01/2005